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Clinical Trial Details
Individualized Assessment and Treatment for Marijuana Dependence: Treatment Mechanisms
Clinical Trial ( IRB ) #: 12-174-3
Title: Individualized Assessment and Treatment for Marijuana Dependence: Treatment Mechanisms
Principal Investigator: Dr. Mark Litt
Description: Marijuana is the most commonly used illicit drug in the US, but treatment for marijuana dependence is not fully effective. The most effective treatments to date have employed motivational enhancement (MET) plus cognitive-behavioral coping skills treatment (CB) and contingency management (CM) for abstinence. In the current study we are exploring the idea that more tailored teaching of coping skills may result in improved outcomes for marijuana-dependence than those seen thus far. The Individualized Assessment and Treatment Program (IATP) for marijuana dependent patients will employ experience sampling (ES) to determine the strengths and weaknesses of each patient in drug-use situations so that treatment can be tailored accordingly. Participants will be 275 men and women meeting criteria for marijuana dependence and randomly assigned to 9 sessions of treatment in one of 4 treatment conditions: Standardized MET plus CB (SMET-CB); SMET+ CM (SMET-CB-CM); IATP; or IATP + CM (IATP-CM). Patients in all treatments will engage in ES via cell-phone for two weeks prior to treatment, for a weekly period during treatment, for another week after treatment has ended, and for two weekly periods at months 8 and 14. The data collected will shed light on the ways in which patients in treatment use coping skills in real-time contexts. Finally, the use of repeated ES periods will allow us to determine how treatment impacts thoughts, feelings and behaviors, and how these in turn affect outcome in the long and short term. We expect that all treatments will prove effective for reducing marijuana use.
  Addiction/Substance Abuse
Eligibility Criteria: Check with study contact
How to Contact: Elise Kabela-Cormier. Telephone: Toll Free (866) 895-5727. Email: Kabela@uchc.edu
Enrollment Status/Comments: Enrolling/recruiting. For current recruitment status, please check with study contact.
Web Address: clinicaltrials.gov/show/NCT02030665