99-226-1
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Cutanenous Immune Response in Secondary Syphilis and Lyme Disease
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Dr. Juan Salazar
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This study involved three separate sub-studies: 1) Lipopeptide injection: this component of the study demonstrated the contribution of synthetic lipopeptides in triggering the immune response in humans, these synthetic lipopeptides mimic spirochetal lipoproteins; 2) Secondary syphilis patients: this component of the study was conducted in order to better understand the pathogenesis of early syphilis and to determine how syphilis can set the stage for acquiring and transmitting HIV; 3) Healthy volunteer blood draw: These experiments are primarily conducted to study the effects of two spirochetes (Borrelia burgdorferi and Treponema pallidum). The only portion of the study that remains open is the healthy blood draw; the international and national sites have finalized their recruitment and no patients are being followed, data from these patients is currently under data analysis.
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Infectious Disease/Immune System
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Check with study contact
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Slawa Gajewska. Telephone: (860) 679-3445. Email: gajewska@uchc.edu
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Enrolling/recruiting. For current recruitment status, please check with study contact.
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