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Bone Loss, Physical Function and Frailty in Older Women with Sickle Cell Trait
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22-327-1
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Bone Loss, Physical Function and Frailty in Older Women with Sickle Cell Trait
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Dr. Biree Andemariam
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This research study has two purposes. The first purpose is to determine whether having sickle cell trait is a risk factor for the development of bone thinning in older women. Nearly 10% of African Americans carry sickle cell trait, and most of them are unaware of it. African Americans are less likely to develop thin bones than whites, but if they sustain a bone fracture, they are more likely to die from it. Having sickle cell trait may lead to bone thinning and predispose a subset of African Americans to dangerously thin bones. The second purpose is to investigate whether women with SCT have reduced decreased muscle function, decreased muscle mass, and increased frailty compared to women without SCT. Frailty is a common clinical syndrome in older adults that carries an increased risk for poor health outcomes, including falls, incident disability, hospitalization, and death. This study will try to fill a knowledge gap in the scientific literature. It may potentially reveal a previously unrecognized risk factor for disability and address potential health disparity in African descent women.
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Blood - Sickle Cell Disease
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Muscle, Bone and Cartilage
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Women’s Health (Infertility, Menopause, Etc.)
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Check with study contact
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Sasia-Marie Jones. Telephone: Not available. Email: sajones@uchc.edu
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Enrolling/recruiting. For current recruitment status, please check with study contact.
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