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Clinical Trials: Sleep Disorders
IRB No. 18X-148-2: Sleep Apnea and Diastolic Dysfunction (SADD) Study
Obstructive sleep apnea (OSA) is strongly associated with a number of cardiovascular diseases including hypertension, atrial fibrillation, coronary artery disease, and heart failure. Hypothesis: Obstructive sleep apnea is linked to diastolic heart failure as evident by echocardiographic evidence of diastolic dysfunction. Aims of this study are (1) to determine whether OSA is associated with diastolic dysfunction by comparing the echocardiographic parameters between the subjects with abnormal sleep study and those with normal sleep study;(2) to determine if the severity of OSA as evaulated by the sleep study is associated with the degree of diastolic dysfunction; (3) to determine whether left atrial strain imaging as a part of diastolic dysfunction parameters closely correlates to the severity of OSA.