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Clinical Trials: Brain, Spinal Cord and Nervous System
IRB No. 10-273S-2 (Dr. Robert Clark, PI): The Role of Unique Lipids Derived From Common Human Bacteria in Multiple Sclerosis
Study description not available
IRB No. 19-214S-1 (Dr. David Steffens, PI): Apathy and Reward Systems in Alzheimer's Disease
Apathy is a common feature of Alzheimer';s disease (AD) that is related to functional decline, but its underlying neurobiology is poorly understood. In this application, we propose to use functional magnetic imaging and tasks that focus on the brain';s reward system to examine apathy in AD and in late-life depression. Our aim is to identify new targets for intervention to improve apathy in patients with AD.
IRB No. 25-160-2 (Dr. Hardeep Singh, PI): Recovery Kinetics Following Surgical Treatment for Degenerative L4-5 Spondylolisthesis: A pilot and Feasibility Study
Specific Aim(s) Evaluate recovery kinetics in patients undergoing lateral lumbar interbody fusion via prone approach + minimally invasive posterior spinal fusion (LLIF + PSF), minimally invasive transforaminal lumbar interbody fusion via tubular based retractor (MIS TLIF + PSF), and open transforaminal lumbar interbody fusion (Open TLIF + PSF) through monitoring step count during hospital stay and post operatively using a wearable fitness tracker. Compare length of stay, narcotic consumption, radiographic parameters, and fusion between groups outlined above.