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Clinical Trials: Psychiatry - General Adult/Mental Health (Depression, Anxiety, Etc.)
IRB No. 16-055-2 (Dr. David Steffens, PI): Department of Psychiatry: Adult Repository
The purpose of the repository is to prospectively collect biological samples along with clinical data to facilitate future research studies and pilot analysis related to medical and behavioral health research.
IRB No. 22-287-2 (Dr. Kevin Manning, PI): Apathy: An Early Manifestation of Frailty and Disability in Older Adults with Depression?
The overall objective of this research is to understand whether a subtype of depression in older adults - apathy - heralds the onset of disability. This pilot project will test the hypotheses that there will be differences in functional performance and blood-based biomarkers between older depressed adults with and without apathy.
IRB No. 25-378S-2 (Dr. Jennifer Kanaan, PI): A Volunteer-Facilitated Intensive Care Unit (ICU) Diary Program- A Pilot Study
This pilot study aims to implement and evaluate a volunteer-facilitated Intensive Care Unit (ICU) Diary Program at UConn Health's John Dempsey Hospital. ICU diaries are a low-cost communication tool that helps patients process their critical illness experience and potentially reduce symptoms of Post-Intensive Care Syndrome (PICS), which affects 50-70% of ICU survivors with cognitive impairments, psychiatric illness, and physical limitations. Our research will explore how undergraduate student volunteers can facilitate the implementation of ICU diaries by maintaining daily entries about patients' ICU experiences in simple, non-medical language. We will recruit approximately 30 adult ICU patients and 40 ICU staff members over a 12-week period. Patients will receive diaries during their ICU stay, with entries made by volunteers, staff, and family members. Follow-up phone calls at 3 months after discharge will gather feedback on patients' experiences with the diaries. Staff pre and post implementation surveys will be administered to evaluate staff perceptions of volunteer integration. The findings from this research may help establish a sustainable model for implementing volunteer-facilitated ICU diary programs in settings with limited resources. This knowledge is important because while ICU diaries have shown benefits in reducing PICS symptoms in European healthcare settings, they have not been widely adopted in the US due to staffing and resource constraints. A volunteer-facilitated approach may provide an accessible way to deliver this evidence-based communication tool to improve long-term outcomes for critically ill patients.